In addition, changes in phosphorylated or total CK2 and NR2B expression have not been investigated in relation to phosphorylated tau in the context of other tauopathies, such as corticobasal degeneration (CBD), progressive supranuclear palsy (PSP), and Pick’s disease (Pick’s). The gene discussed is GRIN2B; the disease is supranuclear palsy, progressive, 1.