Among those genes, MAP3K11 (also known as MLK3) is positively associated with the CAD risk (OR: 1.07, 95%CI: 1.05–1.10, Pcausal = 8.46 × 10–9) and is a target of the experimental compound URMC-099 [45]. The gene discussed is MAP3K11; the disease is coronary artery disorder.