UBE4B and neoplasm: Several other putative tumor suppressors in the chromosome 1p or 11q deletion regions including CHD5 [15, 48], UBE4B [13], CADM1 [49], and ATM [50], have patterns that are similar to KIF1B, where a subset of samples exhibit strong ASE in the absence of deletions (Additional file 1: Fig. S4).