However, GSDMC and GSDMD had high homozygous amplification frequencies in ovarian serous cystadenocarcinoma (OV), oesophageal carcinoma (ESCA), uterine carcinosarcoma (UCS), breast invasive carcinoma (BRCA), stomach adenocarcinoma (STAD), liver hepatocellular carcinoma (LIHC), and uveal melanoma (UVM). The gene discussed is GSDMC; the disease is ovarian serous cystadenocarcinoma.