NFKB2 and acute myeloid leukemia: Furthermore, when AML cells were cocultured with gilteritinib and NF-κB2 siRNA, the protein levels of NKG2DLs were significantly lower than those in cells incubated with gilteritinib alone (Fig. 6D), indicating that silencing NF-κB2 hampers the gilteritinib-induced upregulation of NKG2DLs at the protein level.