FLT3scFv/NKG2D CAR T cells also showed certain cytotoxicity against different FLT3mut− AML cell lines (K562 and U937 cells) (Supplementary Fig. 4), while FLT3scFv/NKG2D CAR T cells revealed more killing activity against FLT3 mut+AML cell lines. The gene discussed is KLRK1; the disease is acute myeloid leukemia.