We performed RNAseq analysis of three groups: 1-in vitro wild type CD4+ activated lymphocytes [n = 3], 2-in vitro NPM-ALK-engineered CD4+ lymphocytes [n = 3] and 3-in vivo-derived CD4+ lymphoma cells purified by flow cytometry to isolate CD3+ [n = 3] and CD3- populations [n = 3]. Here, ALK is linked to lymphoma.