In addition, ATP-binding cassette subfamily A member 1 (ABCA1), chitinase-3-like protein I (CH3L1/YKL-40), and NACHT, LRR and PYD domains-containing protein 3 (NLRP3) are neuroinflammatory biomarkers linked to AD [1, 19, 50]. The gene discussed is ABCA1; the disease is Alzheimer disease.