The positive correlation between CD4 counts with RBC, Hgb and HCT among MHC could be explained most likely by the fact that decreased CD4 count as HIV disease progresses could cause anemia by myelosuppression from HIV that impairs erythropoietin [47, 48], malaria may also induce removal of parasitized RBC [49]. This evidence concerns the gene CD4 and anemia (phenotype).