This study found that humanHSCARG protein increased EF, FS, and LVEF levels, reduced plaque volume, LVEDd,and LVESd levels, inhibited SCr and BUN levels, decreased urine concentrationand MDA levels, and promoted SOD, GSH, and GSH-PX levels in mice models of CHD(Figure 2). This evidence concerns the gene SOD1 and coronary artery disorder.