To analyze the effects and mechanism of HSCARG in CHD, we used invitro model to confirm the antioxidant effects of HSCARG.Overexpression of HSCARG reduced ROS production and MDA levels, and increasedSOD, GSH-PX, and GSH levels in the in vitro model (Figure 3A-3F). This evidence concerns the gene NMRAL1 and coronary artery disorder.