BIN1 and centronuclear myopathy: An insertion of the SINE retrotransposon in HACD1 exon 2 is associated with CNM in Labrador Retrievers (Pele et al., 2005), and missense and splice site mutations in MTM1 and BIN1 were respectively shown to cause CNM in Labrador Retrievers, Rottweilers, Boykin Spaniels, and Great Danes (Beggs et al., 2010; Bohm et al., 2013; Olby et al., 2020; Shelton et al., 2015).