SLC25A13 and citrin deficiency: Citrin deficiency was previously thought to be a rare hereditary disease restricted to the Japanese population but is now considered a pan-ethnic disease that is prevalent in East Asia.[8,9] The calculated frequency of homozygotes from the carrier rates (1/112) of mutations in SLC25A13 among Koreans is 1/50,000,[9] suggesting the likelihood of hospitals encountering surgical patients with citrin deficiency in Korea.