In addition, the patient exhibited liver function impairment with high levels of alanine aminotransferase and aspartate aminotransferase, and it was confirmed that the liver is one of the most frequently involved organs in HPS.[10] The PET-CT scan showed extensive bone damage and an increased standard uptake value; therefore, we suspected a possible malignancy, especially lymphoma. The gene discussed is GPT; the disease is Hermansky-Pudlak syndrome.