Consistent with this hypothesis, a previous study showed that the downregulation of FASN by cisplatin [also known as cis‐diamminedichloroplatinum (II) or CDDP] triggered irreversible DNA damage and continuous apoptosis in MDA‐MB‐231 breast cancer cells, regardless of exogenous fatty acid supplementation [42]. The gene discussed is FASN; the disease is breast cancer.