The two Treg states were differentiated by higher expression of Il2ra, Tnfrsf4, Tnfrsf9, and Tnfrsf18 in CD4IL2RAHI cells, which was observed in our data (Figure 10B,C) and published data on human bladder tumors.[18] Mito‐ATO treatment significantly changed the percentages of some CD4+ T cell clusters in the mouse tumors (Figure 10D). The gene discussed is TNFRSF18; the disease is urinary bladder neoplasm.