ITSN1 and Cognitive impairment: For example, prior research presents that lnc‐ITSN1‐2 correlates with increased CRP, Ranson's score, APACHE II score in SAP patients16; meanwhile, lnc‐ITSN1‐2 positively associates with cognitive impairment, CRP, TNF‐α and IL‐17 levels in AIS patients.22