We also determined effects of amino acids on ALL cells with endogenous KRAS mutations (CEM and KOPN8) (Tate et al., 2019) and observed that the relative growth rates of these cells were also more sensitive to concentration changes of extracellular amino acids in comparison with Reh cells (with endogenous wild-type KRAS) (Figure S1). Here, KRAS is linked to acute lymphoblastic leukemia.