Plasma transfusion is an essential component of treatment for many congenital and acquired coagulopathies in dogs, such as disseminated intravascular coagulopathy, hemophilia A (deficiency of factor VIII), hemophilia B (deficiency of factor IX), von Willebrand's disease, hepatic disease, or anticoagulant rodenticide toxicity (8–10). The gene discussed is F9; the disease is hyperinsulinemic hypoglycemia, familial, 4.