Another commonly reported parameter that infers the procoagulant state of COVID-19 patients is the imbalance of von Willebrand factor (vWF) and ADAMTS13 (cleaves ultra-large vWF multimers), as evidenced by increased vWF antigen levels and decreased ADAMTS13 activity in hospitalized COVID-19 patients’ plasma (Favaloro et al., 2021). The gene discussed is ADAMTS13; the disease is COVID-19.