IL6 and respiratory failure: As an important mediator of CRS, IL-6 appears to be correlated to respiratory failure (Jørgensen et al., 2020; Leisman et al., 2020; Moore and June 2020), acute respiratory distress syndrome (Leisman et al., 2020; Moore and June 2020), and adverse clinical outcomes(Del Valle et al., 2020; Moore and June 2020).