FABP4 and breast cancer: In addition, FABP5 is highly expressed in TAMs infiltrating breast cancer, which is associated with lipid droplet accumulation and secretion of immunostimulatory cytokines, including IL-6 FABP4 is upregulated in macrophage infiltration in late-stage breast cancer, which supports tumor progression by favoring IL-6 expression through NFκB-miR-29b pathway signaling (40).