CUL3 and cancer: Further studies showed that the same NRF2 pathway-related gene was significantly associated with immune-related scores in various cancers; especially, FOS, FOSL1 and MAF were positively associated with immune-related scores in various cancers, and CUL3, GSK3B, KEAP1, and MAPK8 were negatively associated with immune-related scores in various cancers.