SST and vascular neoplasm: In addition, we analyzed the relationships between the SST methylation and clinical phenotypes, and the results showed that methylation of the SST CpG sites in 1stExon could be related to differentiation status, lymph node metastasis status, vascular tumor thrombus status, and infiltration depth, suggesting that hypermethylation of the CpG sites in the SST 1stExon region may influence the tumor biological behavior of GIT cancers.