GSE8511 database analysis result showed that compared to normal tissues, HK2, PFKFB3, SLC2A1, PGK1, PKM2, and LDHA were upregulated, and PGAM1, SLC2A3, and LDHB were downregulated in PCa (Figure 1(a)). The gene discussed is PGK1; the disease is posterior cortical atrophy.