GSE8511 database analysis result showed that compared to normal tissues, HK2, PFKFB3, SLC2A1, PGK1, PKM2, and LDHA were upregulated, and PGAM1, SLC2A3, and LDHB were downregulated in PCa (Figure 1(a)). Here, PGAM1 is linked to posterior cortical atrophy.