We observed a similar result that HK2, SLC2A1, LDHA, PFKFB2, TPI1, and ENO1 were upregulated, while PFKFB3, ALDOA, PGAM1, SLC2A3, and LDHB were downregulated in PCa compared to those in normal prostate tissues (Figure 2). The gene discussed is PFKFB3; the disease is posterior cortical atrophy.