We observed a similar result that HK2, SLC2A1, LDHA, PFKFB2, TPI1, and ENO1 were upregulated, while PFKFB3, ALDOA, PGAM1, SLC2A3, and LDHB were downregulated in PCa compared to those in normal prostate tissues (Figure 2). This evidence concerns the gene PFKFB2 and posterior cortical atrophy.