AKT1 and malaria: The most upregulated DEGs were significantly enriched in hsa05143 (African trypanosomiasis), hsa05144 (malaria), and hsa05150 (Staphylococcus aureus infection), and the downregulated DEGs were mainly enriched in hsa05144 (malaria), hsa04151 (PI3K-Akt signaling pathway), and hsa04350 (TGF-beta signaling pathway).