Using a candidate gene approach, from a cohort of 237 adult Vietnamese TB patients, Caws et al. concluded that individuals carrying the C allele of the Toll-like receptor-2 (TLR2) T597C polymorphism were significantly more likely to develop TB caused by mycobacteria belonging to the East-Asian/Beijing strain family [OR = 1.57 (95% CI 1.15–2.15)] (Caws et al., 2008). Here, TLR2 is linked to tuberculosis.