A similar effect was observed in a study comparing NK-like CARs (NKG2D TM and 2B4 + CD3ζ intracellular domains) and T-like CARs (CD28 TM and 4-1BB + CD3ζ intracellular domains), which showed that iPSC-derived NK cells expressing NK-like CARs induced tumor regression and prolonged mice survival (113). The gene discussed is CD247; the disease is neoplasm.