CD4 and nonpapillary renal cell carcinoma: At the same time, we found that the levels of several immune cell infiltration appeared to correlate with altered copy number of OIP5 gene, including B cell, CD4+T cell, CD8+T cell, NK cell, T cell regulatory (Tregs), Neutrophil, Monocyte, Mast cell activated and Endothelial cell in ccRCC (Figure 7).