CRTC1 and obesity disorder: Taken together these observations suggest that: (1) the association of CRTC1 locus with obesity markers is stronger when reliable markers of adiposity (such as BF%) are used, (2) it may exist a sex-specific effect, even though, the use of different CRTC1 SNPs and different sample populations (general population versus psychiatric cohorts) complicate the interpretation of these GWAS studies.