Recent findings have also associated MeCP2 with neurodegenerative diseases, including Alzheimer’s, Parkinson’s, and Huntington’s diseases (Ausió et al., 2014), in which astrocytes undergo atrophy and asthenia affecting their homeostatic and protective functions (Verkhratsky and Nedergaard, 2018). This evidence concerns the gene MECP2 and juvenile Huntington disease.