To evaluate the effect of ABT-199 in vivo, we performed xenograft experiments by transplanting patient-derived blastic MDS-L cells26, which have a CMP immunophenotypic profile (Supplementary Fig. 8a) and a high level of BCL-2 expression (Extended Data Fig. 9d), into sublethally irradiated NSGS mice (Supplementary Fig. 8b). Here, BCL2 is linked to myelodysplastic syndrome.