HLA-C and asthma: We found that only two of the six variants were associated with a clinical risk factor: the MHC variant was associated with asthma (P = 6.8 × 10−9) and type 2 diabetes (T2D) (P = 1.5 × 10−5), while the ABO variant was associated with kidney disease (P = 1.4 × 10−4) and T2D (P = 9.7 × 10−5; Supplementary Table 8).