Only GAL-9 exhibited increased gene and surface expression in every human B-ALL cell line tested, and this was induced by both adipocyte-secreted factors (Fig. 5a, b and Supplementary Fig. 7a, b) and in adipocyte co-culture assays (Fig. 5c and Supplementary Fig. 7c). This evidence concerns the gene LGALS9 and precursor B-cell acute lymphoblastic leukemia.