Based on our Luminex and ELISA analyses of the adipocyte and stromal cell secretomes (Supplementary Fig. 2a–c), we chose to determine whether GAL-9 surface expression on human B-ALL cells was regulated by cytokines secreted at significantly higher levels by adipocytes than by bone marrow stromal cells (Supplementary Fig. 2a-c and 8a). The gene discussed is LGALS9; the disease is precursor B-cell acute lymphoblastic leukemia.