The levels of myelinated fiber markers, including myelin basic protein (MBP), myelin-associated glycoprotein (MAG), and neurofilament marker neurofilament 200 (NF200), were all significantly reduced after stroke (Fig. 1G, H; P < 0.001 for MBP, P = 0.0068 for MAG, P = 0.0175 for NF200), which was further verified by immunoblotting (Fig. 1I, J; both P = 0.001). The gene discussed is MBP; the disease is Stroke.