Our results indicated that high expression level of LPAR2 was significantly associated with a worse OS in patients with ACC (HR = 2.35[1.08 − 5.11], P = 0.031), KIRC (HR = 1.99 [1.46 − 2.71], P < 0.001) and MESO (OS, HR = 1.74 [1.08 − 2.81], P = 0.023) (Fig. 5 J, L, M). The gene discussed is LPAR2; the disease is adrenal cortex carcinoma.