By using GEPIA2 tool, we acquired the top 100 genes which had similar expression patterns with LMNB1 in the combined data of all TCGA cancer types, and the most six correlated genes are TMPO (thymopoietin) (R = 0.81), KIF11 (kinesin family member 11) (R = 0.79), NUSAP1 (nucleolar and spindle associated protein 1) (R = 0.79), KIF15 (kinesin family member 11) (R = 0.78), MCM6 (minichromosome maintenance complex component 6) (R = 0.77), PLK4 (R = 0.77) (Fig. 5A). This evidence concerns the gene PLK4 and cancer.