Though previous reports indicated that LMNB1 was downregulated in breast cancer by qRT-PCR [17], gastric cancer [18], lung adenocarcinoma and squamous cell carcinoma by IHC staining [19], TCGA analysis indicated LMNB1 expression in the above 4 tumor kinds was upregulated at least in the mRNA level. This evidence concerns the gene LMNB1 and squamous cell carcinoma.