In addition, high TNF-α (P<0.001, adjusted P <0.001), IL-1β (P=0.033, adjusted P=0.132), and IL-6 (P=0.012, adjusted P=0.048), but not IL-17 (P=0.554, P=1.000 after adjustment) were correlated with cognition impairment occurrence (Figure 2A-H). The gene discussed is IL17A; the disease is Cognitive impairment.