TNF and Anxiety: Furthermore, high TNF-α (P<0.001, adjusted P <0.001) and increased IL-17 (P=0.014, adjusted P=0.056), but not IL-1β (P=0.648, adjusted P=1.000) or IL-6 (P=0.131, adjusted P=0.524), were correlated with increased anxiety severity grade (Figure 3A-L).