Based on our observations, we propose the following putative series of events in EoE tissue remodelling: the EMT phenomenon may be induced by chronic inflammation brought about by the EoE disease state, likely secondary to hypersensitivity reaction leading to activation of the aforementioned inflammatory response via the NF-κB or TGF-β pathways [12, 13]. Here, TGFB1 is linked to eosinophilic esophagitis.