YBX1 and glioblastoma: Surprisingly, the protein levels of YB-1 in 8 glioblastoma tissues were dramatically upregulated compared with those in paired adjacent tissues (Figure 1A), while the mRNA levels of YB-1 did not show significant changes between glioblastoma and adjacent tissues (Figure 1B), suggesting that aberrant overexpression of YB-1 in glioblastoma predominantly takes place at the protein level.