CD4 and colonic neoplasm: Previous studies suggested that ARID1A mutations are likely to be related to the higher immune infiltrates in endometrial cancer, stomach cancer and colon cancer.22 In addition, in our previous study,10 we noticed that the expression of ARID1A and ARID1B is closely associated with the abundance of TILs, including CD4 + T cells and CD8 + T cells.