DLC1 was negatively associated with prognosis in LUAD, with a hazard ratio of 0.68, which is consistent with studies showing its suppressive activity in LUAD cells,41, 42 Expression of KAT2B is decreased in many cancers, and KAT2B can regulate SHC3, an immune‐related gene that is associated with the prognosis of LUAD.43, 44. This evidence concerns the gene SHC3 and cancer.