For instance, ZPR1 (Galcheva-Gargova et al., 1998; Corton et al., 2000) and BUD13 (Brooks et al., 2009) were well-documented for lipid level, HERPUD1 was found related to HDL-C in the Korean population (Oh et al., 2020), and the APOA5 and CETP also showed evidence of contributing to triglycerides, metabolic syndrome, and HDL-C (Talmud et al., 2009; Lin et al., 2016). The gene discussed is ZPR1; the disease is metabolic syndrome.