There are many genetic risk factors for PD, such as mutations to the SNCA gene that lead to the formation of α-synuclein aggregates known as Lewy bodies (Schulz-Schaeffer, 2010; Mahul-Mellier et al., 2020), as well as mutations to the PINK1 and parkin genes that lead to failed mitophagy (the managed intracellular degradation of dysfunctional mitochondria), neuronal defects and even apoptosis (Goldberg et al., 2003; Palacino et al., 2004; Wood-Kaczmar et al., 2008). Here, PRKN is linked to Parkinson disease.