Two of the CVR scores described above (Table 1) take into consideration additional clinical information contributing to CVR burden relevant for patients with ARDs, such as a previous diagnosis of rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) and concomitant steroid treatment (the QRISK3 and QRISK-lifetime scores) (36) and only one includes the high sensitivity C-reactive protein (hsCRP) levels (RSS) (38). This evidence concerns the gene CRP and systemic lupus erythematosus.