Moreover, individuals with the ALDH2 rs671-AA genotype exhibit severely decreased activity of the ALDH2 enzyme and an elevated level of gamma-glutamyl transpeptidase (GGT) in patients with non-alcoholic fatty liver disease (NAFLD) (14), indicating that the polymorphism of ALDH2 might have an important influence on liver diseases. Here, GGTLC1 is linked to metabolic dysfunction-associated steatotic liver disease.