Regarding the paired tumor and adjacent normal tissues in TCGA cohort, we observed that ISYNA1 was over-expressed in 10 cancers, such as BRCA, CHOL, ESCA, HNSC, LIHC, LUAD, LUSC, STAD, THCA, and BLCA (Figures 2A–J). Here, ISYNA1 is linked to cancer.