In our study, we first assessed the expression of ISYNA1 and found the elevated ISYNA1 expression in 12 among 33 cancers types, including BLCA, BRCA, CHOL, COAD, ESCA, GBM, HNSC, LIHC, LUAD, LUSC, STAD, and THCA. Here, ISYNA1 is linked to cancer.