Recently, nuclear medical imaging techniques, including positron emission tomography (PET), single photon emission computed tomography (SPECT), and multimodal imaging, have been considered for assessing PD-1/PD-L1 expression of diverse tumor types (Bensch et al., 2018; Gao et al., 2020; Lv et al., 2020). Here, CD274 is linked to neoplasm.