Existing research works have addressed MIF as being implicated in the pathogenesis of various inflammatory and autoimmune diseases, including sepsis (Bozza et al., 2004), rheumatoid arthritis (Kim et al., 2011), diabetes (Sanchez-Zamora et al., 2010), solid tumors and cancer (Nobre et al., 2017), acute respiratory distress syndrome (Donnelly et al., 1997), hepatic inflammatory diseases (Marin et al., 2017), multiple sclerosis (Benedek et al., 2017), systemic lupus erythematosus (Tu et al., 2019), psoriasis (Bezdek et al., 2018), and dengue (Chuang et al., 2015). Here, MIF is linked to acute respiratory distress syndrome.