Interestingly, we identified that poor prognosis of GC was correlated with higher SPI1 expression: overall survival (OS) hazard ratio (HR) = 1.9, 95% confidence interval (CI) = 1.55 to 2.33, P = 4.3e-10; progression free survival (PFS) HR = 1.84, 95% CI = 1.49 to 2.27, P = 1.2e-08; post-progression survival (PPS) HR = 2.44, 95% CI = 1.93 to 3.08, P = 1.3e-14) (Figures 2A–C). This evidence concerns the gene SPI1 and gastric cancer.