To further clarify the relationship between YQHY and ferroptosis, we selected ACSL4, which is closely related to ferroptosis, as the target of this topic, and the JAK2–STAT3 pathway as the pathway of this topic to explore whether YQHY could induce ferroptosis in GC by influencing the expression of ACSL4, JAK2, and STAT3. This evidence concerns the gene JAK2 and gastric cancer.