Multivariate analysis was performed in GSE102349 and the result showed that CDCA8 (HR = 1.23, 95% CI = 1.01–1.5) and CDCA3 (HR = 1.14, 95% CI = 1.02–1.3) were independent risk factors for prognosis in NPC (Figure 4, p < 0.05). Here, CDCA8 is linked to nasopharyngeal carcinoma.